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Characterization factor is another variable suggested
2020-11-17

Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain e
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br Discussion The present results demonstrate that
2020-11-17

Discussion The present results demonstrate that high dose estrogen–progestogen OC treatment produced impaired glucose tolerance and glucose tolerance was preserved during low dose estrogen–progestogen, high or low dose progestogen-only OC use. The study also shows that impaired glucose tolerance
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br Results and discussion br Conclusions
2020-11-17

Results and discussion Conclusions In conclusion, we have developed rational strategies that allowed us to successfully identify a series of novel analogs structurally related to to modulate the activity of estrogen-related receptors (ERRγ and ERRβ), which are constitutively active. All of th
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br Materials and methods br Results and
2020-11-17

Materials and methods Results and discussion Concluding remarks Together, the results of the theoretical kinetic simulations and of the analysis of the experimentally determined kinetic data of SoBADH performed in this work show that ignoring substrate inhibition causes potentially importan
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ACE also known as Kininase II is an important enzyme
2020-11-17

ACE also known as Kininase II is an important enzyme of the Renin angiotensin Evodiamine system (RAAS) (Novo et al., 1987), it is believed to be a potent blood pressure regulator and also plays a crucial role in activation of the bradykinin receptor via inactivation of bradykinin which works to indu
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The genes corresponding to TVAG TVAG TVAG TVAG and
2020-11-17

The genes corresponding to TVAG_263740, TVAG_487600, TVAG_282090, TVAG_170370, and TVAG_148010 seem to be the less expressed, and undetectable by proteomics approach. In comparison, in other T. vaginalis strains, and experimental conditions, they show very few or null EST's reports [4]. Concludin
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We had earlier reported that collagen fibers
2020-11-16

We had earlier reported that collagen fibers with intact native banded structure were occasionally observed in the kinase-deficient, membrane-anchored DDR2 ECD (DDR2/-KD) samples; however, in our DDR1/ECD and DDR2/ECD samples, observation of native banded structure of collagen was far more infrequen
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Our approach including the characterization of histone modif
2020-11-16

Our approach, including the characterization of histone modifications in scarce NK subsets, allowed us to identify super-enhancers, which associate with genes endowing a given cell type with its unique identity (Hnisz et al., 2013). Especially intriguing were SEs with distinct activities in NK subse
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br Results br Discussion Oxysterols and EBI have
2020-11-16

Results Discussion Oxysterols and EBI2 have received growing attention in the field of immunology, with works highlighting an important role for EBI2 in immune cell migration. However, these studies are mainly limited to animal models (Chalmin et al., 2015, Hannedouche et al., 2011, Kelly et a
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In a study carried out by Aunis
2020-11-16

In a study carried out by Aunis et al. the properties of soluble DBH and membrane bound were examined [23]. The membrane bound enzyme was shown in bcrp inhibitor to the soluble form to have thermal denaturation at higher temperatures of 43.5–44°C. Similar discontinuities in the Arrhenius plots were
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To date many studies have reported significant
2020-11-16

To date, many studies have reported significant aberrant methylation patterns in TIMPs in various types of cancer hexokinase inhibition [[16], [17], [18]]. However, little has been reported on the events that lead to the methylation of TIMPs in the UV-irradiated human skin. Therefore, the objective
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Preparation of the regioisomeric pyridooxazepinones and was
2020-11-16

Preparation of the regioisomeric pyridooxazepinones 10 and 11 was accomplished utilizing the synthetic sequence depicted in Scheme 3. Amide coupling of 63 and Trovafloxacin mesylate australia chloride 64 afforded amide 65. Removal of the alcohol protecting group, followed by base catalyzed cyclizat
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The recombinant Scl collagen system has shown
2020-11-16

The recombinant Scl2 collagen system has shown capability as a biomaterial as well because of its adaptability and scalability. Scl2 was functionalized to crosslink into a hydrogel without disrupting its triple helix [130]. The Scl2–hydrogel crosslinking also did not disrupt cell adhesion and integr
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br Acknowledgements br Introduction Lung cancer
2020-11-16

Acknowledgements Introduction Lung cancer treatment strategies, especially molecular targeted therapy, have progressed rapidly. However, most established treatments are for adenocarcinoma of the lung, not for squamous cell carcinoma (SQCC). SQCC constitutes approximately 30% of lung cancers, w
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An even more striking difference is observed when
2020-11-16

An even more striking difference is observed when comparing active site residues, which are evolutionarily very well conserved in other soluble PPases 18, 19. In 31 known PPase sequences, 13 functionally important active site residues are conserved in all sequences, but only two of them (D70 and D97
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